Ozempic vs. Orlistat
Ozempic and Orlistat differ fundamentally in their mechanism and results. Ozempic, a GLP-1 agonist, improves blood sugar and offers moderate weight loss, while Orlistat, a lipase inhibitor, blocks fat absorption for modest weight loss. Ozempic is approved for type 2 diabetes and cardiovascular risks, while Orlistat targets weight loss and weight management only. Side effects differ significantly: Ozempic causes nausea, whereas Orlistat is linked to gastrointestinal issues like oily stools. Ozempic costs $875/month, far exceeding Orlistat’s $100/month. Neither faces current shortages.
Slows gastric emptying, reduces appetite, and enhances feelings of fullness, leading to lower calorie intake. It also stimulates insulin release and reduces glucagon secretion, improving blood sugar control.
Common Side Effects
Nausea, vomiting, diarrhea, constipation, and abdominal pain.
Serious Potential Side Effects
Pancreatitis, gallbladder issues, kidney problems, and increased heart rate, thyroid cancer, anaphylaxis (or serious allergic reactions)
Blocks the breakdown and absorption of dietary fat in the intestines. Unabsorbed fat is excreted in the stool, reducing calorie intake and promoting weight loss.
Common Side Effects
Oily or fatty stools, frequent bowel movements, flatulence with discharge, and abdominal discomfort.
Serious Potential Side Effects
Rare liver damage and malabsorption of fat-soluble vitamins (A, D, E, K), kidney problems, and severe allergic reactions