Ozempic vs. Trulicity
Ozempic and Trulicity, both GLP-1 receptor agonists, are indicated for type 2 diabetes and cardiovascular event risk reduction. Ozempic achieves superior HbA1c reductions and greater weight loss effects compared to Trulicity. Both drugs are used off-label for weight management. Side effects, including nausea, overlap, though Trulicity may cause additional fatigue. Ozempic costs $875/month, comparable to Trulicity’s $875/month. Neither drug currently faces shortages.
Slows gastric emptying, reduces appetite, and enhances feelings of fullness, leading to lower calorie intake. It also stimulates insulin release and reduces glucagon secretion, improving blood sugar control.
Common Side Effects
Nausea, vomiting, diarrhea, constipation, and abdominal pain.
Serious Potential Side Effects
Pancreatitis, gallbladder issues, kidney problems, and increased heart rate, thyroid cancer, anaphylaxis (or serious allergic reactions)
Slows gastric emptying, reduces appetite, and enhances feelings of fullness, leading to lower calorie intake. It also stimulates insulin release and reduces glucagon secretion, improving blood sugar control.
Common Side Effects
Nausea, diarrhea, vomiting, fatigue, and decreased appetite.
Serious Potential Side Effects
Pancreatitis, thyroid tumors (potential risk), gallbladder issues, kidney problems, and serious allergic reactions